e-Prints Soton - Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription

Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription ... Transfection of the p53 gene with an alanine mutation at the Ser315 site into...
http://eprints.soton.ac.uk/26221/

 

Cancer Cell International |Full text |P53 and Beta-Catenin Activity during Estrogen treatment of Osteoblasts

Skip to main content / 11-Dec-2007  / Home | ... Nuclear p53 localization was detected in several cells. ... P53 function was monitored by measuring CAT activity in ROS-PG-13 cells. ... The patterns...
http://www.cancerci.com/content/5/1/24

 

T YOSHIMOTO et al.: p53 mutations in adrenal tumours (Journal of Endocrinology)

... Immunohistochemical staining demonstrated that two of three cases with missense mutations and one case with an intronic sequence alteration over- expressed p53 protein in tumour cell nuclei. We observed no association...
http://journals.endocrinology.org/joe/159/joe1590247.htm

 

Journal of Negative Results in BioMedicine |Full text |CP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on

... Other p53 target genes prevent the process of angiogenesis [2]. ... Direct interaction and stabilization of p53 is not excluded. ... But p53 levels increase after treatment...
http://www.jnrbm.com/content/3/1/5

 

ErbB2 (Her-2) and p53 antibodies for cancer study: News from AnaSpec

Laboratorytalk / The latest news for scientists and laboratory professionals ... One of the most important mammalian cell cycle checkpoint proteins is the tumor suppressor protein, p53. In normal, undamaged cells,...
http://www.laboratorytalk.com/news/anp/anp120.html

 

Journal of Translational Medicine |Full text |Immunologic aspect of ovarian cancer and p53 as tumor antigen

Skip to main content / 9-Dec-2007  / Home | ... p53 as tumor ... P53 as tumor ... P53 as tumor ... ... P53 is a tumor suppressor protein. ...
http://www.translational-medicine.com/content/3/1/34

 

Study of hypoxia and new gene reveals early-stage action of p53 tumor suppressor gene

Forum for Science, Industry and Business ... Composite of action of Buip3L and p53 under hypoxia. ... The gene is turned on by p53 and a second transcription factor called hypoxia inducible factor, or...
http://www.innovations-report.com/html/reports/life_sciences/report-38436.html

 

Virology Journal |Full text | p53 represses human papillomavirus type 16 DNA replication via the viral E2 protein

Skip to main content / Log on / register / BioMed Central home | ... Figure 3. p53 represses E2-induced transcription. ... Figure 4. p53 inhibits DNA replication mediated by E2. ... Here we have shown...
http://www.virologyj.com/content/5/1/5

 

Breast Cancer Research |Full text | p53 protein accumulation predicts resistance to endocrine therapy and decreased post-relapse survival in metastatic breast

Skip to main content ... (b) Post-relapse survival according to p53 protein accumulation. ... HER2 overexpression and p53 protein accumulation significantly reduced post-relapse survival. ... The...
http://breast-cancer-research.com/content/8/4/R48

 

David Meek ; Biomedical Research Centre

Biomedical Research Centre / David W Meek / Reader / Regulation of the p53 tumour suppressor network ... To understand the molecular basis of the signalling mechanisms that regulate the p53 response.
http://www.dundee.ac.uk/biomedres/meek.htm

 
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