p53 Phosphorylation Assay

Fluorescent Cell-Based Assay for Determination of p53 vs Phospho-p53 (Sponsored Link)
http://www.Cellomics.com/

 

P53 Tumor Suppressor

95% Pure, Full-Length, Custom Recombinant Proteins & Antibodies (Sponsored Link)
http://www.ProteinOne.com/

 

Pathway & Focused Arrays

p53 Pathway Microarrays & Service Whole Genome solutions available (Sponsored Link)
http://www.phalanxbiotech.com/

 

p53 apoptosis

New qPCR technology Analyze Apoptosis Pathway (Sponsored Link)
http://www.SABiosciences.com/

 

Ovarian cancer linked to p53 gene -- Mayor 315 (7100): 75 -- BMJ

... This may lead to mutations in the p53 gene, which normally stops cells from proliferating into cancer. Previous research has shown that p53 mutation occurs in around half of all cases of ovarian...
http://www.bmj.com/cgi/content/full/315/7100/75/d

 

Tsai, Mol Vis 2005; 11:50-55.

... P53 protein levels in these cells were also evaluated by IHC. ... The primers used for p53 gene sequencing are listed in Table 1. ... Skilling JS, Sood A, Niemann T, Lager DJ, Buller RE. An...
http://www.molvis.org/molvis/v11/a5/

 

Untitled Document

DEPARTMENT OF BIOLOGY ... Rubbi C.P. and Milner J. p53 - guardian of a genome's guardian? Cell Cycle. 2: 20-21. ... Milner J. DNA damage, p53 and anticancer therapies. Nat. ... Milner J. Flexibility:...
http://www-users.york.ac.uk/~ajm24/welcome1.html

 

World Journal of Surgical Oncology |Full text |Evidence that the p53 negative / Bcl-2 positive phenotype is an independent indicator of good prognosis in colo

18-May-2007  / '); //--> > / Home | / Browse articles | / Search | ... Frequencies of immunohistochemical expression of p53 and Bcl-2. ... Co-expression of p53 with Bcl-2. ... In this study...
http://www.wjso.com/content/3/1/47

 

Regulation of p53 nuclear export through sequential changes in conformation and ubiquitination -- Nie et al., 10.1074/jbc.M610515200 -- Journal of Biological Ch

... Wild-type p53 is a conformationally-labile protein that undergoes nuclear-cytoplasmic shuttling. ... Mutant p53 ubiquitination occurred at lysines in both the DNA-binding domain (DBD) and...
http://www.jbc.org/cgi/content/abstract/M610515200v1

 

72pp issue.indd

... The tumour suppressor role of p53 requires its nuclear activation and retention. ... 5. Kastan MB. Participation of p53 protein in the cellular response to DNA damage. ... 8. Levine AJ.
http://www.rcsed.ac.uk/Journal/vol47_4/47400002.html

 

Actin Inhibition: The identification of PTX-2 as a novel anti-mitotic agent that selectively induces apoptosis in p53 deficient cancer cells

... In addition p53 target genes activate cell cycle checkpoints and induce apoptosis. ... The ability of p53 mutations to disrupt this checkpoint allows cells to become resistant to agents such as...
http://www.bioportfolio.com/LeadDiscovery/PubMed-060504.html

 

Theoretical Biology and Medical Modelling |Full text |Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against can

Skip to main content / 18-Dec-2007  / Home | ... Levine AJ: P53, the cellular gatekeeper for growth and division. ... Vousden KH, Lu X: Live or let die: the cell's response to p53. ... Vogelstein B,...
http://www.tbiomed.com/content/2/1/38

 

Differentiating human keratinocytes are deficient in p53 but retain global nucleotide excision repair following ultraviolet radiation [An article from: DNA Repa

... Following ultraviolet radiation, induction of p53 following ultraviolet radiation was abrogated by 6 days of calcium-induced differentiation. Basal levels of mRNA encoding the DNA damage recognition proteins, XPC and...
http://charles-darwin.classic-literature.co.uk/book-store/B000RR6KIM/Differentiating-human-keratinocytes-are-deficient-in-p53-but-retain-global-nucleotide-excision-repair-following-ultraviolet-radiation-%5BAn-article-from-DNA-Repair%5D.html

 

Dr. Steven Picksley

... My research has focussed on the human p53 tumour supressor, which is inactivated in 50-60 % of all tumours. In the normal cell the p53 tumour suppressor is barely detectable and biochemically...
http://www.brad.ac.uk/staff/smpicksley/SP.html

 
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