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Pharmacologic disruption of Polycomb-repressive co...[Genes Dev. 2007] - PubMed Result

... Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer. ... Silencing of human polycomb target genes is associated with...
http://www.ncbi.nlm.nih.gov/pubmed/17437993/

 

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Home ... Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells. ... Polycomb-repressive complex 2 (PRC2)-mediated histone...
http://www.leaddiscovery.co.uk/articles/17437993/

 

Research - Institute for Cell and Molecular Bioscience - Newcastle University

Skip to Content ... The chrome domain is a sequence motif first recognised in the Drosophila polycomb protein and heterochromatin protein (HP1), two proteins associated with stable and heritable transcriptional silencing. ...
http://www.ncl.ac.uk/camb/research/publication/31560

 

Rogue Stem Cell Study Yields Anti-Cancer Protein

... Normally, polycomb proteins repress genes during development, or when stem cells are needed for tissue maintenance. But an aberrant polycomb spells trouble. In mice where...
http://www.scienceagogo.com/news/20070121024951data_trunc_sys.shtml

 

www.mrc-cpe.cam.ac.uk/~mda201/projects/mbt.html

Home / Useful Links / Publications / Projects / The MBT domain / Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2. ... Sex Comb on Midleg (SCM) belongs to the Polycomb group (PcG) of proteins, which are involved in...
http://www.mrc-cpe.cam.ac.uk/~mda201/projects/mbt.html

 

Assessing the Feasibility of a New Method for Noninvasive Measurement of Endothelial Function in Conduit Arteries.

The role of Bmi-1 in skin development and carcinogenesis / Dr Kirstin Braun / Bmi-1 is a member of the Polycomb group (PcG), a family of epigenetic transcriptional silencers implicated in cancer and maintenance of embryonic...
http://www.smd.qmul.ac.uk/morbidanatomy/intercal/60.html

 

Study Helps Explain Gene Silencing In The Developing Embryo

... "We know that if something is wrong with the Polycomb group, if these genes are mutated and cannot silence Hox, then development becomes abnormal. ... "Basically, we found that the...
http://www.sciencedaily.com/releases/2002/10/021030074400.htm

 

Demethylation of H3K27 Regulates Polycomb Recruitment and H2A Ubiquitination -- Lee et al. 318 (5849): 447 -- Science

Jump to: Page Content, Section Navigation, Site Navigation, Site Search, Account Information, or Site Tools. Note to users. ... Demethylation of H3K27 Regulates Polycomb Recruitment and H2A Ubiquitination ...
http://www.sciencemag.org/cgi/content/figsonly/318/5849/447

 

Staff Contacts

Home | / Contact | / Log into MUSE / Search for ... Polycomb Group and Prostate Cancer: (Collaboration with Dr V. Cunliffe and Prof P. Ingham, Biomedical Sciences), study of the role of the Polycomb...
http://www.shef.ac.uk/medicine/staff/hamdy.html

 

Genome Biology |Full text |Nuclear processes controlled by molecular machines

Skip to main content / Log on / register / BioMed Central home | / Journals A-Z | / Feedback | ... It is known that genes can be silenced epigenetically either by being in close proximity to centromeric heterochromatin (which is permanently...
http://genomebiology.com/2002/3/6/reports/4016

 
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