Ubiquitin & UPP Research

Enzymes, inhibitors, substrates, & kits with product use references (Sponsored Link)
http://www.BostonBiochem.com/products.php/

 

The Caenorhabditis elegans rhy-1 Gene Inhibits HIF-1 Hypoxia-Inducible Factor Activity in a Negative Feedback Loop That Does Not Include vhl-1 -- Shen et al. 17

... Once hydroxylated, HIF-1 binds to the von Hippel–Lindau (pVHL) tumor suppressor, the recognition component of an E3 ubiquitin–protein ligase, and this results in ubiquitination and proteasomal degradation of HIF-1...
http://www.genetics.org/cgi/content/full/174/3/1205

 

Monogenetic Diseases

Home > Molecular Biology > Genes and Diseases / Monogenetic Diseases / Disease Gene Protein Product / Achondroplasia FGFR3 Fibroblast growth factor receptor 3 / Adrenoleukodystrophy ABCD1 ATP-binding cassette (ABC) transporters ... Angelman...
http://www.web-books.com/MoBio/Free/Ch10G.htm

 

Respiratory Research |Abstract |Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts

... We focused on genes not previously found to be regulated by TGFβ in lung fibroblasts or other cell types, including nuclear co-repressor 2, SMAD specific E3 ubiquitin protein ligase 2 (SMURF2), bone morphogenetic protein...
http://respiratory-research.com/content/5/1/24/abstract/

 

Journal of Molecular Signaling |Full text |ArhGAP9, a novel MAP kinase docking protein, inhibits Erk and p38 activation through WW domain binding

16-May-2007  / '); //--> > / Home | / Browse articles | / Search | / Weblinks | / Submit article | / My Journal of Molecular Signaling | / About Journal of Molecular Signaling ... 24. Abriel H, Kamynina E, Horisberger JD, Staub O: Regulation...
http://www.jmolecularsignaling.com/content/2/1/1

 

eMedicine - Prader-Willi Syndrome : Article by Ann ScheimanneMedicine - Prader-Willi Syndrome : Article by

... Several genes have been mapped to the 15q11.2-13 region, including the SNRPN gene, P gene (type II oculocutaneous albinism), UBE3A gene (encodes a ubiquitin-protein ligase involved in intracellular protein turnover), and...
http://www.emedicine.com/ped/topic1880.htm

 

Nutrition & Metabolism |Full text |Effect of prolonged intravenous glucose and essential amino acid infusions on nitrogen balance, muscle protein degradation

Skip to main content / Log on / register / BioMed Central home | / Journals A-Z | / Feedback | / Support / Home | / Browse articles | / Search | / Weblinks | / Submit article | ... Three enzymes are thought to regulate this process: ubiquitin...
http://www.nutritionandmetabolism.com/content/5/1/5

 

Plant Gene Register PGR00-036

PLANT GENE REGISTER PGR00-036 ... Finally, ubiquitin is covalently ligated to the Lys residues of substrate protein via the isopeptide bond by UBC enzyme alone or together with a third enzyme, ubiquitin-protein ligase (E3).
http://www.ebi.ac.uk/~textman/pgr-htdocs/pgr/PGR00-036.html

 

Ontology http://www.mindswap.org/2003/CancerOntology/nciOncology.owl

Ontology http://www.mindswap.org/2003/CancerOntology/nciOncology.owl / Link / http://www.mindswap.org/2003/CancerOntology/nciOncology.owl (hyperdaml) (dumpont) / Description / National Cancer Institute's Ontology of Cancer / Point of Contact / Jim...
http://www.daml.org/ontologies/318

 

New genetic hypothesis for the cause of autism

... They suggest that epigenetic and genetic factors (both de novo and inherited) cause autism through dysregulation of two or more principal genes, one of which maps within chromosomes 15q11-q13, with the Angelman gene encoding E6-AP...
http://www.innovations-report.com/html/reports/life_sciences/report-33315.html

 

The School of Pharmacy: Dr Kirsten Harvey

... Although the majority of PD cases are idiopathic, the identification of disease-causing mutations in the genes for alpha-synuclein (PARK1), the E3 ubiquitin-protein ligase Parkin (PARK2), PINK1 (PARK6), DJ-1 (PARK7) and...
http://www.pharmacy.ac.uk/kirsten_harvey.html

 
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